Being the MGS fan I am I have to say MGS4. However, Starcraft holds a very special place in my heart and I absolutely cannot wait to play Starcraft 2. I think it's time to upgrade the PC.
How come nobody remembers Splinter Cell Conviction?
Once that comes out I fear that I will start failing my classes and slowly start to destroy any trace of a life that I have. My conversations will be about Brawl and nothing else. I shall alienate all who don't play Brawl. Brawl shall own my soul. (ok, maybe it won't go that far, but I can guarantee my grades will start to slip once I get Brawl)
It's a tough decision. I do think I'm looking forward to Brawl most...But Fable 2, Starcraft 2, and Spore are all sharing an equal amount of love in my heart with Brawl...
in all seriousness, I'm really looking forward to MGS4, Final Fantasy XIII/Versus XIII, Devil May Cry 4, GTA 4 if the shooting doesn't suck ass, and Battlefield: Bad Company. also, I KNOW they're going to make somewhat of a sequel to assasin's creed, while there are some things that keep it from being perfect, They could definitely improve upon it with a sequel. It's just too much fun.
I'm not really anticipating anything at the moment, I'm afraid. I think I'm all burnt out with Assasin's Creed, Mass Effect, and COD4 all coming out at once. For a while longer I'll be too busy to think of the future.
Brawl
House of the Dead 2 & 3 (not a 'new game' but I'll buy it upon release)
No More Heroes
I"ve got $36 on a card for Best Buy that I WAS gonna spend last night till I remembered Brawl. That's what its all about. In theory, we get Mario Kart Wii next year too. Ads are already up at Hastings for pre-orders.