Hmm, depends on what you like. I think my favorite is probably Trauma Center, followed by Castlevania. Feel the Magic also has a special place in my heart.
UPDATE: i now officially have a DS lite. My god the thing sure is sexy and it feels great just holding it in your hands. I had it reserved at best buy so i went there and picked it up. I must say i am impressed. The brightness of the screen is much better even than the PSPs screen. There werent really a vast amount of game selections at best buy so i just had to go with metroid prime hunters. I still dont have a Nintendo Wifi connect USB attachment, but i am very eager to get one. The framerate is smooth, the graphics are great, the sound is great, the game is very enjoyable and God the Lite looks very sexy.
it is awesome a good enough size to fit into your pocket. The lite is well worth the money.
I think that the metroid prime multiplayer couldve been better. Once you go online you face random people that you cant communicate with until you have them on your friends and rivals list. The multiplayer couldve been built a little more better. But Nintendo Wi-Fi is easy to use and the game is still enjoyable.
btw: i figured out you dont actually need that USB connector to use wi-fi